Born on 18 August 1947 in the city of Beni Suef, Labib began his journey in acting at the High Cinema Institute, graduating in 1970. His career was delayed for a decade, however, as he joined the military and took part in the October War of 1973, before spending four years abroad.

Upon his return in the early 1980s, Labib quickly left a unique imprint on Egypt’s film, television, and theatre scenes. His talents made him a favourite among directors, especially in comedic roles, where he often appeared alongside stars such as Adel Imam, Mohamed Henidy, Ahmed Helmy, and Ahmed El-Sakka. Over the decades, he built a portfolio that exceeded 300 works.

Some of his best-known film roles include Ga’ana Al-Bayan Al-Taly (Breaking News, 2000), The Embassy in the Building (2005), Morgan Ahmed Morgan (2007), Wahed Sefr (2009), Bobbos (2009), A'ssal Eswed (Molasses, 2010), Zahaimar (2010), Baba (2012), and Mawlana (2017). His most recent films include 2024 productions such as Maasoom, Ana w Ebn Khalti (My Cousin and I), and Al-Sharabiya.

Labib also appeared in over 200 television series, including Al-Malek Farouk (King Farouk, 2007), Al-Aqrab (The Scorpion, 2013), Wanus (2017), Bashtery Ragel (2017), and Awlad Abed (2023), among many others.
His recognizable voice made him a sought-after voice actor for dubbing and narration roles.

While primarily known for screen roles, Labib also appeared on stage on occasion, earning critical acclaim for performances that showcased his live-acting talent and dedication to the craft.